Microbial Metabolomics with Gas Chromatography/Mass Spectrometry
نویسندگان
چکیده
منابع مشابه
Microbial metabolomics with gas chromatography/mass spectrometry.
An analytical method was set up suitable for the analysis of microbial metabolomes, consisting of an oximation and silylation derivatization reaction and subsequent analysis by gas chromatography coupled to mass spectrometry. Microbial matrixes contain many compounds that potentially interfere with either the derivatization procedure or analysis, such as high concentrations of salts, complex me...
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[1] As part of the Large-Scale Biosphere-Atmosphere Experiment in Amazonia (LBA)Cooperative LBA Airborne Regional Experiment (CLAIRE) 2001 campaign in July 2001, separate day and nighttime aerosol samples were collected at a ground-based site in Amazonia, Brazil, in order to examine the composition and temporal variability of the natural ‘‘background’’ aerosol. We used a high-volume sampler to ...
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Microbial metabolomics constitutes an integrated component of systems biology. By studying the complete set of metabolites within a microorganism and monitoring the global outcome of interactions between its development processes and the environment, metabolomics can potentially provide a more accurate snap shot of the actual physiological state of the cell. Recent advancement of technologies a...
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This review presents an overview of the dynamically developing field of mass spectrometry-based metabolomics. Metabolomics aims at the comprehensive and quantitative analysis of wide arrays of metabolites in biological samples. These numerous analytes have very diverse physico-chemical properties and occur at different abundance levels. Consequently, comprehensive metabolomics investigations ar...
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untargeted. Targeted metabolomics focuses on a subset of metabolites involved in one or more pathways; the chemical identities of metabolites to be measured are known, authentic standards are available in these studies. The goal of untargeted metabolomics is to observe global metabolite profiling differences between sample types, experiments are designed to maximise the coverage of metabolites....
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ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2006
ISSN: 0003-2700,1520-6882
DOI: 10.1021/ac060521q